About Adele

My name is Adele, and I hope to use my technical skills to advance immunological research through methods development, computational modeling, and data analysis. I am currently a Computational Biology Ph.D. student in the Department of Computer Science at the Johns Hopkins University, where I am advised by Dr. Rachel Karchin. My reserach focuses on multiomics data integration and machine learning to improve immunogenic neoepitope prediction, with the goal of advancing personalized cancer immunotherapy. At present, personalized cancer vaccines are only available for a small subset of patients through clinical trials, and even then, the anti-tumor immune response rates are not always robust. By improving neoantigen prediction algorithms together with many other scientists in the field, I hope that our collective efforts will lead to more effective and accessible cancer immunotherapies.

Prior to joining the Karchin Lab, I worked with Dr. Yana Safonova at Hopkins for a year on genomics analysis of immunoglobulin loci across mammals. I earned my B.Sc. (Hons) in Biomedical Infomatics from Zhejiang University-University of Edinburgh Institute. My Honours thesis was on in-silico mutagenesis of KRAS protein, where I was advised by Dr. Xianghua Li.